WordPress is the backend of most of the blogs on the internet, the only reason of WordPress popularity is open source. This results in support from developers of world wide. WordPress has maximum number of plugins & themes and developers have already started exploring possibilities of desktop application for WordPress.
One such desktop application is here, WordPress Comments Notifier. WordPress Comments Notifier is written in QT/C++ that alerts you when new comments are posted on your WordPress blog (works well with WordPress MU too), It displays an icon in your system tray to let you know if you have new comments, It also has features that allow you to manage/reply/edit comments directly from your desktop.
WordPress Comments Notifier
This application can be useful for those bloggers who don’t want their reader to wait for comment to be live and also want comment moderation power. With Wp Comments Notifier comment moderation task will become extremely convenient and also no need of staying logged into your inbox to get new comment alert.